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Test Code PROTC Protein C Activity, Plasma

Methodology

Amidolysis of Chromogenic Substrate

Performing Laboratory

Huntsville Hospital Laboratory

Specimen Requirements

1. Draw blood in a blue-top (citrate) tube(s). Spin down, remove plasma, spin plasma again, and place 1 mL of citrate platelet-poor plasma in plastic vial. (Glass vial is not acceptable.)

Note:  Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.
2. Freeze specimen immediately at ≤-40° C, if possible.
3. Send specimen frozen.
Note:  1. Each coagulation assay requested should have its own vial.
2. If the patient is being treated with Coumadin®, this should be noted. Coumadin® will lower protein C.
3. Heparin >2 U/mL may interfere with this assay.
4. Lipemic specimen may be rejected.

Reference Values

Adults:  70-130%

Day(s) Test Set Up

Tuesday, Friday

CPT Coding

85303

Secondary ID

HHA1242

LOINC Coding

Test Name LOINC Code

Protein C Activity, Plasma

52767-1

 

Specimen Stability Information

 

Specimen Type

Temperature

Time

Platelet-poor plasma,citrated

RT, spun

4 hrs

  Frozen 2 weeks