Test Code NFLP Neurofilament Light Chain, Plasma
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Lavender top (EDTA)
Acceptable: None
Submission Container/Tube: Plastic screw-top vial
Specimen Volume: 0.6 mL
Collection Information: Centrifuge and aliquot plasma into a plastic vial. Do not submit specimen in original tube.
Useful For
Assessing neuronal damage related to various neurodegenerative diseases
Method Name
Chemiluminescent Enzyme Immunoassay
Reporting Name
Neurofilament Light Chain, PSpecimen Type
EDTA PlasmaSpecimen Minimum Volume
0.50 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
EDTA Plasma | Refrigerated (preferred) | 14 days |
Frozen | 90 days | |
Ambient | 7 days |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | OK |
Reference Values
<2.5 years: ≤12.8 pg/mL
2.5 to 4 years: ≤11.8 pg/mL
5 to 9 years: ≤10.4 pg/mL
10 to 14 years: ≤8.8 pg/mL
15 to 19 years: ≤9.2 pg/mL
20 to 24 years: ≤10.4 pg/mL
25 to 29 years: ≤11.9 pg/mL
30 to 34 years: ≤13.5 pg/mL
35 to 39 years: ≤15.3 pg/mL
40 to 44 years: ≤17.3 pg/mL
45 to 49 years: ≤19.7 pg/mL
50 to 54 years: ≤22.4 pg/mL
55 to 59 years: ≤25.4 pg/mL
60 to 64 years: ≤28.8 pg/mL
65 to 69 years: ≤32.7 pg/mL
70 to 74 years: ≤37.1 pg/mL
75 to 79 years: ≤42.1 pg/mL
80 to 84 years: ≤ 47.8 pg/mL
≥85 years: ≤54.3 pg/mL
Day(s) Performed
Monday through Friday
Report Available
1 to 3 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83884
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
NFLP | Neurofilament Light Chain, P | 101281-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
NFLP | Neurofilament Light Chain, P | 101281-4 |
Forms
If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen.