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HelpTest Code MEPHS Mephobarbital and Phenobarbital, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 2.0 mL
Collection Instructions:
1. Collect specimen immediately before next scheduled dose.
2. Centrifuge and aliquot serum into plastic vial within 2 hours of collection.
Useful For
Monitoring of mephobarbital and phenobarbital therapy
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MBARS | Mephobarbital, S | No | Yes |
| PHBRS | Phenobarbital, S | No | Yes |
Method Name
Gas Chromatography Mass Spectrometry (GC-MS)
Reporting Name
Mephobarbital and Phenobarbital, SSpecimen Type
Serum RedSpecimen Minimum Volume
0.7 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days | |
| Ambient | 14 days | ||
| Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
MEPHOBARBITAL
Therapeutic range: 1.0-7.0 mcg/mL
Toxic concentration: ≥15.0 mcg/mL
PHENOBARBITAL
Therapeutic range
Children: 15.0-30.0 mcg/mL
Adults: 20.0-40.0 mcg/mL
Toxic concentration: ≥60.0 mcg/mL
Day(s) Performed
Thursday
Report Available
3 to 9 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80184
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MEPHS | Mephobarbital and Phenobarbital, S | 97183-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 89706 | Mephobarbital, S | 3750-7 |
| 84582 | Phenobarbital, S | 3948-7 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.