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HelpTest Code LEFLU Leflunomide Metabolite (Teriflunomide), Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Draw blood no sooner than 12 hours (trough value) after last dose.
2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Useful For
Therapeutic monitoring of patients actively taking leflunomide
Assessment of elimination in patients requiring enhanced elimination of the drug
Method Name
High-Turbulence Liquid Chromatography Mass Spectrometry (HTLC-MS/MS)
Reporting Name
Leflunomide Metabolite, SSpecimen Type
Serum RedSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Ambient (preferred) | 28 days | |
| Frozen | 28 days | ||
| Refrigerated | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Therapeutic: >40 mcg/mL
Elimination: <0.020 mcg/mL
Day(s) Performed
Monday, Wednesday, Friday
Report Available
3 to 5 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80193
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| LEFLU | Leflunomide Metabolite, S | 44828-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 60292 | Leflunomide Metabolite, S | 44828-2 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.