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Test Code ESTS Estradiol, Rapid, Immunoassay, Serum


Ordering Guidance


This assay is for reproductive assessment (eg, IVF, conception). For other clinical indications, order EEST / Estradiol, Serum.

 

The preferred method for measurement of low serum estradiol concentrations in children, males, and postmenopausal females is liquid chromatography-tandem mass spectrometry (LC-MS/MS), order EEST / Estradiol, Serum.

 

This test should not be used when monitoring estradiol concentrations in patients being treated with Fulvestrant due to possible cross-reactivity. In these patients, estradiol concentrations should be measured using mass spectrometry; order EEST / Estradiol, Serum.



Specimen Required


Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Useful For

Rapid assessment of ovarian status, including follicle development, for assisted reproduction protocols (eg, in vitro fertilization)

 

Establishing time of ovulation and optimal time for conception

Method Name

Electrochemiluminescent Immunoassay (ECLIA)

Reporting Name

Estradiol Rapid, Immunoassay, S

Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 180 days
  Refrigerated  5 days
  Ambient  24 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

Males: 10-40 pg/mL

Females

Premenopausal: 15-350 pg/mL*

Postmenopausal: <10 pg/mL

*Estradiol concentrations vary widely throughout the menstrual cycle

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

82670

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ESTS Estradiol Rapid, Immunoassay, S 2243-4

 

Result ID Test Result Name Result LOINC Value
ESTS Estradiol Rapid, Immunoassay, S 2243-4