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Test Code CBC Complete Blood Cell Count (CBC) with Differential, Blood


Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.


Useful For

Screening tool to confirm a hematologic disorder, to establish or rule out a diagnosis, to detect an unsuspected hematologic disorder, or to monitor effects of radiation or chemotherapy

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
DIFFR Morphology Eval (special Smear) No No
PINTP Peripheral Smear Interpretation No No

Testing Algorithm

Testing begins with an automated 5-part differential. If manual differential is needed, it will be reflexed and performed if specimen is 24 hours or less post-draw.

 

If the automated 5-part differential is invalid or when abnormal results are identified upon microscopic evaluation, a morphology evaluation is performed at an additional charge. If the smear morphology is adequate and confirms the results of the automated 5-part differential, the automated differential results will be verified and reported.

 

If pathologist expertise is needed for clinically significant diagnosis, a peripheral blood smear review is performed at an additional charge.

Method Name

RF/DC (Radio Frequency/Direct Current) Detection/Hydrodynamic Focusing (DC Detection), Flow Cytometry (Using a Semiconductor Laser)/Sodium Lauryl Sulfate (SLS) Hemoglobin

Reporting Name

CBC with Differential, B

Specimen Type

Whole Blood EDTA

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated (preferred) 48 hours
  Ambient  24 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK
Clotted Reject

Reference Values

Red blood cell count (RBC)

Males:

0-14 days: 4.10-5.55 x 10(12)/L

15 days-4 weeks: 3.16-4.63 x 10(12)/L

5 weeks-7 weeks: 3.02-4.22 x 10(12)/L

8 weeks-5 months: 3.43-4.80 x 10(12)/L

6 months-23 months: 4.03-5.07 x 10(12)/L

24 months-35 months: 3.89-4.97 x 10(12)/L

3-5 years: 4.00-5.10 x 10(12)/L

6-10 years: 4.10-5.20 x 10(12)/L

11-14 years: 4.20-5.30 x 10(12)/L

15-17 years: 4.30-5.70 x 10(12)/L

≥18 years: 4.35-5.65 x 10(12)/L

 

Females:

0-14 days: 4.12-5.74 x 10(12)/L

15 days-4 weeks: 3.32-4.80 x 10(12)/L

5 weeks-7 weeks: 2.93-3.87 x 10(12)/L

8 weeks-5 months: 3.45-4.75 x 10(12)/L

6 months-23 months: 3.97-5.01 x 10(12)/L

24 months-35 months: 3.84-4.92 x 10(12)/L

3-5 years: 4.00-5.10 x 10(12)/L

6-10 years: 4.10-5.20 x 10(12)/L

11-14 years: 4.10-5.10 x 10(12)/L

15-17 years: 3.80-5.00 x 10(12)/L

≥18 years: 3.92-5.13 x 10(12)/L

 

Hemoglobin

Males:

0-14 days: 13.9-19.1 g/dL

15 days-4 weeks: 10.0-15.3 g/dL

5 weeks-7 weeks: 8.9-12.7 g/dL

8 weeks-5 months: 9.6-12.4 g/dL

6 months-23 months: 10.1-12.5 g/dL

24 months-35 months: 10.2-12.7 g/dL

3-5 years: 11.4-14.3 g/dL

6-8 years: 11.5-14.3 g/dL

9-10 years: 11.8-14.7 g/dL

11-14 years: 12.4-15.7 g/dL

15-17 years: 13.3-16.9 g/dL

≥18 years: 13.2-16.6 g/dL

 

Females:

0-14 days: 13.4-20.0 g/dL

15 days-4 weeks: 10.8-14.6 g/dL

5 weeks-7 weeks: 9.2-11.4 g/dL

8 weeks-5 months: 9.9-12.4 g/dL

6 months-35 months: 10.2-12.7 g/dL

3-5 years: 11.4-14.3 g/dL

6-8 years: 11.5-14.3 g/dL

9-10 years: 11.8-14.7 g/dL

11-17 years: 11.9-14.8 g/dL

≥18 years: 11.6-15.0 g/dL

 

Hematocrit

Males:

0-14 days: 39.8-53.6%

15 days-4 weeks: 30.5-45.0%

5 weeks-7 weeks: 26.8-37.5%

8 weeks-5 months: 28.6-37.2%

6 months-23 months: 30.8-37.8%

24 months-35 months: 31.0-37.7%

3-7 years: 34-42%

8-11 years: 35-43%

12-15 years: 38-47%

16-17 years: 40-50%

≥18 years: 38.3-48.6%

 

Females:

0-14 days: 39.6-57.2%

15 days-4 weeks: 32.0-44.5%

5 weeks-7 weeks: 27.7-35.1%

8 weeks-5 months: 29.5-37.1%

6 months-23 months: 30.9-37.9%

24 months-35 months: 31.2-37.8%

3-7 years: 34-42%

8-17 years: 35-43%

≥18 years: 35.5-44.9%

 

Mean corpuscular volume (MCV)

Males:

0-14 days: 91.3-103.1 fL

15 days-4 weeks: 89.4-99.7 fL

5 weeks-7 weeks: 84.3-94.2 fL

8 weeks-5 months: 74.1-87.5 fL

6 months-23 months: 69.5-81.7 fL

24 months-35 months: 71.3-84.0 fL

3-5 years: 77.2-89.5 fL

6-11 years: 77.8-91.1 fL

12-14 years: 79.9-93.0 fL

15-17 years: 82.5-98.0 fL

≥18 years: 78.2-97.9 fL

 

Females:

0-14 days: 92.7-106.4 fL

15 days-4 weeks: 90.1-103.0 fL

5 weeks-7 weeks: 83.4-96.4 fL

8 weeks-5 months: 74.8-88.3 fL

6 months-23 months: 71.3-82.6 fL

24 months-35 months: 72.3-85.0 fL

3-5 years: 77.2-89.5 fL

6-11 years: 77.8-91.1 fL

12-14 years: 79.9-93.0 fL

15-17 years: 82.5-98.0 fL

≥18 years: 78.2-97.9 fL

 

Red cell distribution width (RDW)

Males:

0-14 days: 14.8-17.0%

15 days-4 weeks: 14.3-16.8%

5 weeks-7 weeks: 13.8-16.1%

8 weeks-5 months: 12.4-15.3%

6 months-23 months: 12.9-15.6%

24 months-35 months: 12.5-14.9%

3-5 years: 11.3-13.4%

6-17 years: 11.4-13.5%

≥18 years: 11.8-14.5%

 

Females:

0-14 days: 14.6-17.3%

15 days-4 weeks: 14.4-16.2%

5 weeks-7 weeks: 13.6-15.8%

8 weeks-5 months: 12.2-14.3%

6 months-23 months: 12.7-15.1%

24 months-35 months: 12.4-14.9%

3-5 years: 11.3-13.4%

6-17 years: 11.4-13.5%

≥18 years: 12.2-16.1%

 

White blood cell count (WBC)

Males:

0-14 days: 8.0-15.4 x 10(9)/L

15 days-4 weeks: 7.8-15.9 x 10(9)/L

5 weeks-7 weeks: 8.1-15.0 x 10(9)/L

8 weeks-5 months: 6.5-13.3 x 10(9)/L

6 months-23 months: 6.0-13.5 x 10(9)/L

24 months-35 months: 5.1-13.4 x 10(9)/L

3-5 years: 4.4-12.9 x 10(9)/L

6-17 years: 3.8-10.4 x 10(9)/L

≥18 years: 3.4-9.6 x 10(9)/L

 

Females:

0-14 days: 8.2-14.6 x 10(9)/L

15 days-4 weeks: 8.4-14.4 x 10(9)/L

5 weeks-7 weeks: 7.1-14.7 x 10(9)/L

8 weeks-5 months: 6.0-13.3 x 10(9)/L

6 months-23 months: 6.5-13.0 x 10(9)/L

24 months-35 months: 4.9-13.2 x 10(9)/L

3-5 years: 4.4-12.9 x 10(9)/L

6-17 years: 3.8-10.4 x 10(9)/L

≥18 years: 3.4-9.6 x 10(9)/L

 

Platelet count

Males:

0-14 days: 218-419 x 10(9)/L

15 days-4 weeks: 248-586 x 10(9)/L

5 weeks-7 weeks: 229-562 x 10(9)/L

8 weeks-5 months: 244-529 x 10(9)/L

6 months-23 months: 206-445 x 10(9)/L

24 months-35 months: 202-403 x 10(9)/L

3-5 years: 187-445 x 10(9)/L

6-9 years: 187-400 x 10(9)/L

10-13 years: 177-381 x 10(9)/L

14-17 years: 139-320 x 10(9)/L

≥18 years: 135-317 x 10(9)/L

 

Females:

0-14 days: 144-449 x 10(9)/L

15 days-4 weeks: 279-571 x 10(9)/L

5 weeks-7 weeks: 331-597 x 10(9)/L

8 weeks-5 months: 247-580 x 10(9)/L

6 months-23 months: 214-459 x 10(9)/L

24 months-35 months: 189-394 x 10(9)/L

3-5 years: 187-445 x 10(9)/L

6-9 years: 187-400 x 10(9)/L

10-13 years: 177-381 x 10(9)/L

14-17 years: 158-362 x 10(9)/L

≥18 years: 157-371 x 10(9)/L

 

Neutrophils, absolute

Males:

0-14 days: 1.60-6.06 x 10(9)/L

15 days-4 weeks: 1.18-5.45 x 10(9)/L

5 weeks-7 weeks: 0.83-4.23 x 10(9)/L

8 weeks-5 months: 0.97-5.45 x 10(9)/L

6 months-23 months: 1.19-7.21 x 10(9)/L

24 months-35 months: 1.54-7.92 x 10(9)/L

3-5 years: 1.60-7.80 x 10(9)/L

6-16 years: 1.40-6.10 x 10(9)/L

17 years: 1.80-7.20 x 10(9)/L

≥18 years: 1.56-6.45 x 10(9)/L

 

Females:

0-14 days: 1.73-6.75 x 10(9)/L

15 days-4 weeks: 1.23-4.80 x 10(9)/L

5 weeks-7 weeks: 1.00-4.68 x 10(9)/L

8 weeks-5 months: 1.04-7.20 x 10(9)/L

6 months-23 months: 1.27-7.18 x 10(9)/L

24 months-35 months: 1.60-8.29 x 10(9)/L

3-5 years: 1.60-7.80 x 10(9)/L

6-14 years: 1.50-6.50 x 10(9)/L

15-17 years: 2.00-7.40 x 10(9)/L

≥18 years: 1.56-6.45 x 10(9)/L

 

Lymphocytes, absolute

Males:

0-14 days: 2.07-7.53 x 10(9)/L

15 days-4 weeks: 2.11-8.38 x 10(9)/L

5 weeks-7 weeks: 2.47-7.95 x 10(9)/L

8 weeks-5 months: 2.45-8.89 x 10(9)/L

6 months-23 months: 1.56-7.83 x 10(9)/L

24 months-35 months: 1.13-5.52 x 10(9)/L

3-5 years: 1.60-5.30 x 10(9)/L

6-11 years: 1.40-3.90 x 10(9)/L

12-17 years: 1.00-3.20 x 10(9)/L

≥18 years: 0.95-3.07 x 10(9)/L

 

Females:

0-14 days: 1.75-8.00 x 10(9)/L

15 days-4 weeks: 2.42-8.20 x 10(9)/L

5 weeks-7 weeks: 2.29-9.14 x 10(9)/L

8 weeks-5 months: 2.14-8.99 x 10(9)/L

6 months-23 months: 1.52-8.09 x 10(9)/L

24 months-35 months: 1.25-5.77 x 10(9)/L

3-5 years: 1.60-5.30 x 10(9)/L

6-11 years: 1.40-3.90 x 10(9)/L

12-17 years: 1.00-3.20 x 10(9)/L

≥18 years: 0.95-3.07 x 10(9)/L

 

Monocytes, absolute

Males:

0-14 days: 0.52-1.77 x 10(9)/L

15 days-4 weeks: 0.28-1.38 x 10(9)/L

5 weeks-7 weeks: 0.28-1.05 x 10(9)/L

8 weeks-5 months: 0.28-1.07 x 10(9)/L

6 months-23 months: 0.25-1.15 x 10(9)/L

24 months-35 months: 0.19-0.94 x 10(9)/L

3-5 years: 0.30-0.90 x 10(9)/L

6-17 years: 0.20-0.80 x 10(9)/L

≥18 years: 0.26-0.81 x 10(9)/L

 

Females:

0-14 days: 0.57-1.72 x 10(9)/L

15 days-4 weeks: 0.42-1.21 x 10(9)/L

5 weeks-7 weeks: 0.28-1.21 x 10(9)/L

8 weeks-5 months: 0.24-1.17 x 10(9)/L

6 months-23 months: 0.26-1.08 x 10(9)/L

24 months-35 months: 0.24-0.92 x 10(9)/L

3-5 years: 0.30-0.90 x 10(9)/L

6-17 years: 0.20-0.80 x 10(9)/L

≥18 years: 0.26-0.81 x 10(9)/L

 

Eosinophils, absolute

Males:

0-14 days: 0.12-0.66 x 10(9)/L

15 days-4 weeks: 0.08-0.80 x 10(9)/L

5 weeks-7 weeks: 0.05-0.57 x 10(9)/L

8 weeks-5 months: 0.03-0.61 x 10(9)/L

6 months-23 months: 0.02-0.82 x 10(9)/L

24 months-35 months: 0.03-0.53 x 10(9)/L

3-11 years: 0.00-0.50 x 10(9)/L

12-17 years: 0.10-0.20 x 10(9)/L

≥18 years: 0.03-0.48 x 10(9)/L

 

Females:

0-14 days: 0.09-0.64 x 10(9)/L

15 days-4 weeks: 0.06-0.75 x 10(9)/L

5 weeks-7 weeks: 0.04-0.63 x 10(9)/L

8 weeks-5 months: 0.02-0.74 x 10(9)/L

6 months-23 months: 0.02-0.58 x 10(9)/L

24 months-35 months: 0.03-0.46 x 10(9)/L

3-11 years: 0.00-0.50 x 10(9)/L

12-17 years: 0.10-0.20 x 10(9)/L

≥18 years: 0.03-0.48 x 10(9)/L

 

Basophils, absolute

Males:

0-14 days: 0.02-0.11 x 10(9)/L

15 days-7 weeks: 0.01-0.07 x 10(9)/L

8 weeks-35 months: 0.01-0.06 x 10(9)/L

3-17 years: 0.00-0.10 x 10(9)/L

≥18 years: 0.01-0.08 x 10(9)/L

 

Females:

0-14 days: 0.02-0.07 x 10(9)/L

15 days-4 weeks: 0.01-0.06 x 10(9)/L

5 weeks-7 weeks: 0.01-0.05 x 10(9)/L

8 weeks-5 months: 0.01-0.07 x 10(9)/L

6 months-35 months: 0.01-0.06 x 10(9)/L

3-17 years: 0.00-0.10 x 10(9)/L

≥18 years: 0.01-0.08 x 10(9)/L

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

85025

85007 (if appropriate)

85060 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CBC CBC with Differential, B 57021-8

 

Result ID Test Result Name Result LOINC Value
HGB Hemoglobin 718-7
HCT Hematocrit 4544-3
RBC Erythrocytes 789-8
MCV MCV 787-2
RDW RBC Distrib Width 788-0
WBC Leukocytes 6690-2
NEUAA Neutrophils 751-8
LYMAA Lymphocytes 731-0
MONAA Monocytes 742-7
EOSAA Eosinophils 711-2
BASAA Basophils 704-7
PLTC Platelet Count 777-3