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Test Code CALX CALR Mutation Analysis, Myeloproliferative Neoplasm (MPN), Reflex, Varies


Specimen Required


Only orderable as a reflex. For more information see MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL, Varies.


Useful For

Aiding in the distinction between a reactive cytosis and a chronic myeloproliferative disorder

 

Evaluating mutations in CALR in an algorithmic process for the MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL, Varies

Method Name

Only orderable as a reflex. For more information see MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL, Varies.

 

Polymerase Chain Reaction (PCR) and Fragment Analysis

Reporting Name

CALR, Gene Mutation, Exon 9, Reflex

Specimen Type

Varies

Specimen Minimum Volume

Blood and Bone Marrow: 1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Varies 7 days

Reject Due To

Gross hemolysis Reject
Paraffin embedded bone marrow aspirate clot or biopsy blocks, slides, paraffin shavings
Moderately to severely clotted		 Reject

Reference Values

Only orderable as a reflex. For more information see MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL, Varies.

 

An interpretive report will be provided.

Day(s) Performed

Monday through Friday

Report Available

7 to 10 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

81219-CALR (calreticulin) (eg, myeloproliferative disorders), gene analysis, common variants in exon 9

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CALX CALR, Gene Mutation, Exon 9, Reflex 77174-1

 

Result ID Test Result Name Result LOINC Value
36998 Final Diagnosis 22637-3