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Test Code AFPA Alpha-Fetoprotein, Amniotic Fluid


Necessary Information


The following information is required:

1. Estimated due date by ultrasound

2. Collection date

3. Gestational age must be between 13 and 24 weeks; 16 to 18 weeks preferred.

 

If not ordering electronically, provide information on Second Trimester Maternal Screening Alpha-Fetoprotein / Quad Screen Patient Information (T595) and send with specimen.



Specimen Required


Container/Tube: Amniotic fluid container

Specimen Volume: 0.75 mL

Collection Instructions: Do not centrifuge.


Useful For

Screening for open neural tube defects or other fetal abnormalities

 

Follow-up testing for patients with elevated serum alpha-fetoprotein results or in conjunction with cytogenetic testing

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
ACHE_ Acetylcholinesterase, AF Yes No

Testing Algorithm

If alpha-fetoprotein is positive, then acetylcholinesterase will be performed at an additional charge.

Method Name

AFPA: Immunoenzymatic Assay
ACHE_: Polyacrylamide Electrophoresis

Reporting Name

Alpha Fetoprotein, AF

Specimen Type

Amniotic Fld

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Amniotic Fld Refrigerated (preferred) 7 days
  Ambient  7 days

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

< 2.0 multiples of median (MoM)

Day(s) Performed

Monday through Friday

Report Available

2 to 19 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

82106

82013 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AFPA Alpha Fetoprotein, AF 58735-2

 

Result ID Test Result Name Result LOINC Value
6739 Collection Date 58734-5
DAT15 EDD by US Scan 11781-2
6740 Last Menstrual Period (LMP) 8665-2
24233 EDD by LMP 11779-6
24239 GA at Collection by Scan 11888-5
24240 GA at Collection by Dates 11885-1
24234 GA Used 21299-3
9950 Alpha Fetoprotein, AF 1832-5
24241 Results 29595-6
24235 Interpretation 59462-2
24236 Additional Comments 48767-8
24237 Follow up 80615-8
24238 General Test Info 48767-8